dna

healthy living

A Review of 23andMe's DNA Testing Kit

I finally bit the bullet, saved up my pennies, and purchased an item that's been on my wish list for the past year — a DNA Testing Kit from 23andMe.

DNA KitI finally bit the bullet, saved up my pennies, and purchased an item that's been on my wish list for the past year — a DNA Testing Kit from 23andMe.

This innovative contraption made it onto our February Must Haves list, but let me refresh your memory on the details of the test kit.

For $199 (down from their original price tag of $499), 23andMe mails you a kit, which includes detailed step-by-step instructions and the necessary materials. First, you create an online profile at the site and register your kit; then, you just need to spit in the provided tube, and mail it off to a fancy lab for analysis. From just a tiny saliva sample, using the latest DNA technology, scientists extract DNA from cheek cells in your saliva. From there, the DNA is copied multiple times so that it can be used in the genotyping step. Here's a more in-depth, scientific explanation on how the entire DNA analysis process works.

Here's what happens when you get your DNA results.

celebrity homes

Ashton Kutcher Sells His Bachelor Pad to Benefit Charity

Happily married man Ashton Kutcher is saying goodbye to his Hollywood Hills bachelor pad, selling it through an exclusive Zillow.com listing for $2.6 million.

Happily married man Ashton Kutcher is saying goodbye to his Hollywood Hills bachelor pad, selling it through an exclusive Zillow.com listing for $2.6 million.
While I've always suspected that Kutcher was a cool guy, his excellent taste in real estate has confirmed my suspicions. He also definitely has his heart in the right place. The exclusive listing will benefit the Demi and Ashton Foundation (DNA), a nonprofit organization that raises awareness about child sex slavery and helps in the rehabilitation of its victims.

The house itself is absolutely lovely. Kutcher bought it seven years ago for $1 million, and then, with his father's help, extensively renovated the 1954 Craftsman through Duncan McIntosh.

Take a full tour of the house!

Love It or Leave It

DNA Ancestry Portraits: Love 'Em or Leave 'Em?

You guys were totally into the DNA prints I showed you a while back, but this new twist on the DNA print has a decidedly geeky touch.

You guys were totally into the DNA prints I showed you a while back, but this new twist on the DNA print has a decidedly geeky touch. The DNA Ancestry Portrait ($440) from dna11 still has you swabbing your cheek for your DNA, but then it goes farther than mapping your chromosomes to plot your ancestry. dna11 creates a personalized web page that details your family lineage based off of your sample, then links to the page in this QR-code gallery-sized print. Snap a pic of the print using a QR code reader on your cell phone, and you'll be taken to your ancestry website to review. You can find QR code readers in the Android Marketplace, BlackBerry App World, and iTunes store just by searching "QR code reader."

The print itself comes in a number of colors to choose from and would be a great addition to any geeky living room. What do you think?

science

Do Tell: Guess Haiko's Breed Mix Before DNA Results Come Back

First off, I'd definitely call Haiko super cute, but what breeds do you think make up this pooch?

First off, I'd definitely call Haiko super cute, but what breeds do you think make up this pooch? The beloved pet of CasaSugar, she rescued this dog and was told he was Catahoula and Queensland Heeler, since the puppy's owner suspected dad was a heeler. Wisdom Panel is donating a Wisdom Panel Insight Test for us to swab-and-see but I'm asking for your breed guesses before the official DNA results come back.

He's about 45 pounds at nine months old and is long and leggy with white points on the tip of his tail, paws (with spots) and a white blaze. Check out more pics and then leave your best guesses in the comments below!

News

Are You Attracted to Your Opposite?

You might scratch your head when you pass a beauty with a geek (or Paula Abdul with that cartoon cat), but genetics can help to explain the mismatched pairing.

You might scratch your head when you pass a beauty with a geek (or Paula Abdul with that cartoon cat), but genetics can help to explain the mismatched pairing.

A new study claims that people are subconsciously drawn to partners whose DNA is different from their own. Why? The diversification is most likely an evolutionary strategy; offspring tend to turn out better when there's a greater variety of DNA to choose from. In the case of a beauty and a geek, their kid would have a better chance of being hot and smart. (One can only imagine how cute Marilyn and Joe's children would have been!)

While scientists maintain that opposite genes are good for reproduction, untrained people have long claimed that two opposites can complement each other in a relationship. Everyone wins, for example, when one partner loves to cook, while the other one gets pleasure out of doing the dishes.

Are you attracted to your opposite? Have you ever been a Republican dating a Democrat, a slob dating a clean freak, a jock dating an unathletic partner, or an atheist dating a believer? Do certain "opposite" characteristics cross the line into deal-breaker territory?

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fitness gear

Cool or Not: DNA Testing For Athletic Ability

There's a new test in town, and it has me a little worried.

There's a new test in town, and it has me a little worried. Some parents are using a $149 home-analysis test from Atlas Sports Genetics to find out what types of sports their babies may have been born to play. The test involves swabbing the inside of the baby's mouth, and sending the swab to a lab where technicians look for variations of ACTN3, a DNA strand believed by some experts to predict particular athletic skills.

Different versions of the gene can make someone a more talented power-sports player or better suited for stamina-focused endurance sports, though unsurprisingly, there can be mixed results because we get one copy of the ACTN3 gene from each parent. Some sports psychologists and coaches are highly critical of the test and believe steering kids toward certain sports based on genetics is asking for trouble. One coach pointed out the test may measure natural talent but cannot measure an athlete's desire to succeed — just because you're good at something, does not mean you'll have the heart to achieve greatness.

Still, I can see how some parents might argue they are helping their kids by pointing them in the right direction to become accomplished athletes, by virtue of natural abilities. What do you think of this test, is it cool or not?

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Baby

True Confession — My Husband Isn't the Father of Our Son

Weigh in and tell us if you forgive or not forgive this True Confession.

Weigh in and tell us if you forgive or not forgive this True Confession.

"I did a secret DNA test for my son and my husband. Turns out I lied to everyone. I was so sure he wasn't my ex's, but I was wrong. I feel such a strong urge to tell him the truth but it will rip my husband apart. Can I be forgiven for keeping this secret to myself?"

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relationships

Blame It on the Brain

If you've ever blamed a cheating spouse's nether regions for his infidelities, new research has proven that his brain is actually what's to blame.

If you've ever blamed a cheating spouse's nether regions for his infidelities, new research has proven that his brain is actually what's to blame. Swedish scientists have found that men who carry a specific gene variant called allele — which is present in two of every five men — are more likely to experience marital problems and divorce than those who lack this particular variant of a gene. This study also states the following:

Men with two copies of the allele had twice the risk of experiencing marital dysfunction, with a threat of divorce during the last year, compared to men carrying one or no copies. Women married to men with one or two copies of the allele scored lower on average on how satisfied they were with the relationship compared to women married to men with no copies.

As you can see, infidelity is not a simple choice like so many people believe. As funny as it may sound, these findings have actually fueled a debate as to whether or not men should get tested for this gene before walking down the aisle. On the other hand, Helen Fisher, a biological anthropologist at Rutgers University feels that knowing if you have a weak link makes it easier to overcome. For instance, a man who knows he has the allele might be able to ignore the tugs of restlessness he might feel in his relationship and say, "Oh, it is just my DNA, and I am going to ignore it."

Pretty interesting information, huh! If you're single, would you want your future significant other to take a DNA test for this gene? What are your thoughts on this new finding?

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News

Not Guilty! DNA Evidence Clears JonBenet Ramsey's Parents

Nope, your browser hasn't crashed back to 1996 — the Boulder, CO, district attorney has just announced that new DNA tests have cleared JonBenet Ramsey's entire family in the killing of the 6-year-old beauty queen, 12 years ago.

Nope, your browser hasn't crashed back to 1996 — the Boulder, CO, district attorney has just announced that new DNA tests have cleared JonBenet Ramsey's entire family in the killing of the 6-year-old beauty queen, 12 years ago.

The tests point to an "unexplained third party" as the culprit in the crime from DNA left behind in skin cells, one who is presumably still at large.

It's been confirmed that prosecutors no longer consider any member of the Ramsey family to be a suspect, though for years her parents, John and Patsy Ramsey, were thought to be under an "umbrella of suspicion" in the girl's slaying.

For this the DA apologized, saying, "To the extent that this office has added to the distress suffered by the Ramsey family at any time or to any degree, I offer my deepest apology."

Throughout the unsolved murder saga, with suspicion cast on the family, and John Mark Karr inexplicably and falsely confessing to the crime, father John Ramsey has maintained all along that he believes the case will be solved. JonBenet's mother Patsy Ramsey died in 2006 of ovarian cancer at the age of 49.

Considering this new information and the botched initial investigation, will we ever know who killed JonBenet?

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News

Anti-Genetic Discrimination Bill Passes in US Senate

Genetic discrimination is one form of discrimination the US Senate can agree to disagree with.

Genetic discrimination is one form of discrimination the US Senate can agree to disagree with. The Senate has unanimously passed a preemptive anti-discrimination bill, which will prevent employers, unions, and health insurance companies from discriminating using genetic information. Only patients and doctors will have access to tests that reveal predisposition to diseases.

Besides protecting citizens, scientists believe the bill could save lives. With the legal protection, people will more likely pursue genetic testing, and improve their chances of surviving hereditary illnesses like cancer, diabetes, and heart diseases.

Health insurance companies, assured that their current practices would not be threatened, supported the bill, while the US Chamber of Commerce opposed it.

Is discrimination based on pre-existing health conditions, which is common practice today, that much different from discriminating based on a predisposition to a health condition? With the latest legal assurance, would you get your DNA tested to know which diseases you may face in the future?

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