Celebrity Best Friends | YourTango

These two Spanish-speaking ladies are so close they could be sisters! Salma Hayek and Penélope Cruz were amigas long before their first film together, Bandidas, and almost 10 years later, they aren't afraid to be playful with each other and laugh off lesbian rumors stirred up by the paparazzi.

Penélope appeared on The Late Show With David Letterman a few years ago, where she defended a provocative photo showing Penélope playfully grabbing Salma's booty. "You know what they've been saying because of that picture?" Cruz asked. "We are like sisters and we have some sense of humor. We did that in front of 100 photographers. And the story now is that we are lovers. I'm sorry to say, that is not the case!" These saucy and sassy girls definitely have a sense of humor together!